重庆精准生物技术有限公司（Chongqing Precision Biotech Co., Ltd.）系国际先进精准医疗技术团队与国内知名上市公司联合投资的高新技术企业，总投资2.8亿元。目前公司已与国内外10多所顶级研究机构建立良好合作关系，并不断吸引国际著名的精准医学技术研究机构、高等院校前来合作，将最新的技术研究成果在公司孵化、转化和产业化。公司汇集了一批国际一流的精准医学领域专家及泰斗，围绕肿瘤、自身免疫性疾病、代谢性疾病和退行性疾病等影响人类健康的重大科学问题以基因测序、大数据分析的分子诊断技术、肿瘤疫苗、单克隆抗体、干细胞再生医学、靶点药物等精准医疗技术为切入点，开展个体化医疗与研究，完善生命科学研发价值链，服务于人类健康。
Introduction of Chongqing Precision Biotech Co., Ltd
Chongqing Precision Biotech Co., Ltd. is a high and new technology company which jointly invested by an international advanced precision medical technology team and a domestic well-known listed company with total investment of 280 million RMB. It is also the transformation base of Ministry of Science and Technology’s National Center for International Joint Research on Precision Medicine and Biotherapy. At present, our company has already established good relationship with more than 10 top research institutions from domestic and overseas, and continues attracting international well-known precision medical technology research institutions as well as famous colleges. Closely cooperated with them, we could hatch, transform and industrialize the latest technology research results within the company.
1. High-end Research and Development Platform
Our company is headquartered in the High-tech Zone’s Hi-tech Startup Park of Chongqing, and built with the Chongqing Precision Biologic Industrial Technology Research Institute. With an area of 6,000 square meters and a basic R&D center which meets the GLP-standard, this research center has a total of 5 major functional modules: the molecular and virus research platform, the cell research and development platform, the antibody development platform, the in-vitro cellular function evaluation platform, the in vivo animal evaluation platform and etc..It also has an independent technology clinical translation platform to meet the needs for standardization and large-scale of our technologies, so as to link up the downstream clinical technology applications; in the aspect of clinical application, our company has built a cGMP clinical product production and preparation center with an area of 2,000 square meters. This centerhas3 major independent functional modules for production of the clinical-grade level of plasmids, lentivirus and cell productions, respectively. In addition, our company also has a quality management center with an area of 1,000 square meters which consist of the genetic diagnosis platform, cell products testing platform and a biological sample library.
2. Our Advanced Technical Advantages
Through independent research and development and technology introduction, our company now acquires the clinical level of cells, the plasmids and lentivirus production technology, the antibody high-throughput screening and humanization technology, the high memory CAR-T cell culture technology, the cancer stem cell targeting CAR-T cell technology, as well as the new immunosuppressive resistant CAR-T cell technology and other core technologies. We also focus on the development of allogeneic CAR-T cells, micro-environment-induced CAR-T cells and other new CAR-T technologies. Simultaneously, our company has also made a breakthrough in the field of TCR-T and CAR-NK technology. Our team members have already applied for more than 30 patents related to precision medical field, and have published more than100 SCI papers on internationally renowned publications.
Under the strict implementation, our company’s research and development platforms have designed and established according with the guidelines and standards of the national GLP and GMP, and now we have established 5 major research and development and clinical application platforms: the Immune Cell Therapy Technology Basic Research and Development Platform ,the Immune Cell Therapy Products GMP Preparation Platform, the Clinical-grade Plasmid GMP Preparation Platform, the Clinical-grade Lentivirus GMP Preparation Platform and the Quality Control and Sample Library Platform. Through the establishment of a sound quality control system and standardized operating procedures (SOP), we can ensure the company’s product safety and effectiveness.
3. An International Team of Experts
Our company and team members are currently in charge of more than 20scientific research and transformation projects which are all appointed by the national and local governments. We have established the strategic cooperation relationship with Charité-Universitätsmedizin Berlin of German, the University of Texas MD Anderson Cancer Center, the University of Navarra of Spain and many other top international institutions and have formed an exchange mechanism for international experts and domestic talents. We commit to the construction of an international center for precision medical research and translational medicine.Our company pursues the “people-oriented” talent strategy and brings the top biotechnology talents from domestic and overseas in the field of biological treatment together. We now have an R&D team with more than 80 members, including master＇s and doctoral highly educated researchers accounted for more than 80%. Core researchers of the team are all have more than 10-yearresearch experience in precision medicine, so they have solid theoretical foundation and rich practical experience.
4. The Perfect Industrial Layout
Our company follow the national “innovation-driven” development strategy, takes benefiting the entire citizen by health technology as its goal and facilitates the rapid development of precision medical and biological industries as its focus. We set the layout of precision medical scientific discovery, technological invention, industrial development of the entire research and development chain; we invest and establish biological sample bank, biological information analysis platform, gene detection platform, gene editing and screening platform, cell preparation platform, biological medicine pilot platform, testing platform, health management center, clinical treatment center and other research and development platform as well. We are now developing the whole industry chain of precision medical biological resources storage, genetic diagnosis, gene editing, bio-pharmaceutical, health management and clinical treatment as well.